Lift over variants, positions, or intervals from one reference genome to another.

This web interface supports more input formats and requires fewer clicks than existing interfaces like UCSC LiftOver and Ensembl Assembly Converter.

Under the hood, it uses the UCSC liftOver command-line tool for intervals and positions, while for variants it uses a new bcftools plugin which avoids many of the limitations of other liftover tools (particularly for indels) as described in [Genovese 2024]. In all cases, it uses UCSC chain files. Also, the T2T reference version is hs1/T2T-CHM13v2.0.

To submit issues or feature requests, please use broadinstitute/liftover/issues.

more formats...

• Positions:
  chr8:141310715
  chr8-141310715
  chr8   141310715
  
• Variants:
  chr8:141310715 T>G
  chr8-141310715-T-G
  NM_001089.3(ABCA3):c.875A>T (p.Glu292Val)
• Intervals:
  chr8:141310715-141310720
  chr8   141310715   141310720